化学性质:
规格 | 1mg 5mg 10mg |
CAS | 545-84-6 |
别名 | N/A |
化学名 | N/A |
分子式 | C22H28N2O4 |
分子量 | 分子 384.5 |
溶解度 | DMF: 16 mg/ml,DMSO: 16 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.33 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
(-)-Voacangarine is an indole alkaloid originally isolated from V. africana that is cytotoxic to HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 cells (IC50s = 20 μg/ml). It is cytostatic to wild-type S. cerevisiae and cytotoxic to δrad3-e5 and δrad6-1 mutant S. cerevisiae, which are defective in DNA strand break repair and the mutagenic repair pathway, respectively.
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