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抑制剂 > 蛋白酵素 > Asperosaponin Ⅵ
产品名称:
Asperosaponin Ⅵ
型号:
CS-01Y65007
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

20mg

CAS

39524-08-8

别名

Akebia saponin D

化学名

(4aS,6aS,6bR,8aR,9R,10S,12aR,14bS)-(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl 9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-(((2S,3R,4S,5S)-3,4,5

分子式

C47H76O18

分子量

929.1

溶解度

46.45mg/mL in H2O with ultrasonic

储存条件

-20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                             

Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP2/p38 and ERK1/2 pathway[1]. Asperosaponin  inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB[2].

References:

[1]. Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6.

[2]. Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.

 

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签:Asperosaponin  

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