Gemfibrozil 1-O-β-GlucuronideCS-01Y64962_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	500μg 1mg
CAS	91683-38-4
别名	N/A
化学名	N/A
分子式	C21H30O9
分子量	426.5
溶解度	Methanol: Slightly Soluble
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Gemfibrozil 1-O-β-glucuronide is a major metabolite of gemfibrozil that is formed when gemfibrozil undergoes glucuronidation by UDP-glucuronosyltransferase (UGT) 2B7. Gemfibrozil 1-O-β-glucuronide is an inhibitor of the cytochrome P450 (CYP) isoform CYP2C8 (IC50 = 4.1 μM). It is taken up by organic anion transporting polypeptide 1B1 (OATP1B1) in sandwich cultured human hepatocytes (SCHHs) and inhibits cellular uptake of valsartan in MDCK cells expressing OATP1B1 (IC50 = 20.4 μM).

特别提醒：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

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标签：Gemfibrozil 1-O-β-Glucuronide

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抑制剂 > 蛋白酵素 > Gemfibrozil 1-O-β-Glucuronide

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