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Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib .1 It is also a potential impurity in commercial preparations of dasatinib.2

|1. Christopher, L.J., Cui, D., Li, W., et al. Biotransformation of [14C]dasatinib: In vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys. Drug Metab. Dispos. 36(7), 1341-1356 (2008).|2. Plachká, K., ?vec, F., and Nováková, L. Ultra-high performance supercritical fluid chromatography in impurity control: Searching for generic screening approach. Anal. Chim. Acta 1039, 149-161 (2018).

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