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Kresoxim-methyl is a strobilurin fungicide.1 It inhibits conidial germination of V. inaequalis isolates from apple orchards (EC50s = 0.00033-0.0078 mg/L). Kresoxim-methyl also inhibits mycelial growth (EC50 = 0.240 mg/L) and is fungicidal against Saprolegnia (MIC = 1 mg/L).2 It increases intracellular calcium levels and disrupts the mitochondrial membrane potential in mouse cortical cultures in a concentration-dependent manner.3 Kresoxim-methyl is toxic to goldfish (C. auratus; LC50 = 0.807 mg/L).2

1.Fiaccadori, R., Cicognani, E., Alberoni, G., et al.Sensitivity to strobilurin fungicides of Italian Venturia inaequalis populations with different origin and scab controlPest Manag. Sci.67(5)535-540(2011) 2.Hu, X.-G., Liu, L., Hu, K., et al.In vitro screening of fungicidal chemicals for antifungal activity against SaprolegniaJ. World Aquac. Soc.44(4)528-535(2013) 3.Regueiro, J., Olguín, N., Simal-Gándara, J., et al.Toxicity evaluation of new agricultural fungicides in primary cultured cortical neuronsEnviron. Res.14037-44(2015)