L-Phenylalanine is an amino acid, which is widely used in the production of food flavors and pharmaceuticals[1]. L-Phenylalanine binds to the α2δ subunit of voltage-dependent Ca2+ channels, with a Ki value of 980 nM[2].

References:

[1]. Wu WB, et al. Enhancement of l-phenylalanine production in Escherichia coli by heterologous expression of Vitreoscilla hemoglobin. Biotechnol Appl Biochem. 2018 May;65(3):476-483.

[2]. Mortell KH, et al. Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41.

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