Butyryl-L-carnitine-d3 is intended for use as an internal standard for the quantification of butyryl-L-carnitine by GC- or LC-MS. Butyryl-L-carnitine is a butyrate ester of carnitine.1 It is an inhibitor of intestinal transporters, blocking carnitine uptake by the carnitine transporter and glycine transport by the amino acid transporter in human retinal pigment epithelial (HRPE) cells (IC50s = 1.5 μM and 4.6 mM, respectively).

1.Srinivas, S.R., Prasad, P.D., Umapathy, N.S., et al.Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB0,+Am. J. Physiol. Gastrointest. Liver Physiol.293(5)G1046-G1053(2007)

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