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抑制剂 > 蛋白酵素 > AZD5904
产品名称:
AZD5904
型号:
CS-01Y63900
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

25mg 5mg 10mg 50mg 100mg

CAS

618913-30-7

别名

N/A

化学名

N/A

分子式

C10H12N4O2S

分子量

252.29

溶解度

DMSO : 125 mg/mL (495.46 mM)

储存条件

Store at -20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                             

AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.

AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase; >70-fold to a broad panel of other enzymes, ion channels, and receptors. In isolated human neutrophils, 1 μM AZD5904 inhibits PMA stimulated HOCl by >90%[1].

[1]. Myeloperoxidase (MPO) inhibitor.

 

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签:AZD5904 

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