5,6-epoxy-13-cis Retinoic acid is a metabolite of 13-cis retinoic acid. It is formed when 13-cis retinoic acid undergoes cooxidation by prostaglandin H (PGH) synthase in the presence of hydroperoxides or peroxyl radicals. 5,6-epoxy-13-cis Retinoic acid is also a potential impurity found in commercial preparations of 13-cis retinoic acid.

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