规格 | 25mg 50mg 100mg 250mg |
CAS | 2304-89-4 |
别名 | 3-Dehydrocholic Acid |
化学名 | (5β,7α,12α)-7,12-dihydroxy-3-oxo-cholan-24-oic acid |
分子式 | C24H38O5 |
分子量 | 406.6 |
溶解度 | 30mg/mL in DMSO, 30mg/mL in DMF, 30mg/mL in Ethanol |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
3-Oxocholic acid is a secondary bile acid and a metabolite of cholic acid in C. perfringens, a bacteria found in the intestines of mammals and in the environment.[1],[2] 3-Oxocholic acid serum levels increase following ileal transposition surgery in rats.[3]
References
[1]. Wahlstr?m, A., Sayin, S.I., Marschall, H.-I., et al. Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism. Cell Metab. 24(1), 41-50 (2016).
[2]. Macdonald, I.A., Forrest, T.P., Costain, G.A., et al. Identification of 7α-, 12α-dihydroxy-3-oxo cholanoic acid as the major degradation product from cholic by C. perfringens. J. Steroid Biochem. 9(4), 353-358 (1978).
[3]. Yan, K., Chen, W., Zhu, H., et al. The changes of serum metabolites in diabetic GK rats after ileal transposition surgery. Obes. Surg. 29(3), 882-890 (2019).
特别提醒:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
标签:3-Oxocholic Acid
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